GUI Development Python Libraries

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Row number					Tags
1	PySide6 Qt	3,118,201	133	2026-09-14	Qt GUI Development CLI & GUI	→
	Qt for Python offers the official Python bindings for Qt, same as PyQt6 but it's the official binding with different licensing.
	pyside/github.com/pyside/pyside-setup /2026-09-14 /3,118,201 downloads/month
2	pywebview Web-based	1,551,062	6,017	2026-09-14	Web-based GUI Development CLI & GUI	→
	A lightweight cross-platform native wrapper around a webview component.
	r0x0r/github.com/r0x0r/pywebview/ /2026-09-14 /1,551,062 downloads/month
3	PyQt6 Qt	1,545,940	External	—	Qt GUI Development CLI & GUI	→
	Python bindings for the Qt cross-platform application and UI framework.
	www.riverbankcomputing.com/static/Docs/PyQt6/ /1,545,940 downloads/month
4	nicegui Web-based	942,525	16,206	2026-09-14	Web-based GUI Development CLI & GUI	→
	An easy-to-use, Python-based UI framework, which shows up in your web browser.
	zauberzeug/github.com/zauberzeug/nicegui /2026-09-14 /942,525 downloads/month
5	customtkinter Tkinter	733,882	13,545	2026-06-24	Tkinter GUI Development CLI & GUI	→
	A modern and customizable python UI-library based on Tkinter.
	TomSchimansky/github.com/tomschimansky/customtkinter /2026-06-24 /733,882 downloads/month
6	pygobject Desktop	631,609	159	2026-09-11	Desktop GUI Development CLI & GUI	→
	Python Bindings for GLib/GObject/GIO/GTK+ (GTK+3).
	GNOME/github.com/GNOME/pygobject /2026-09-11 /631,609 downloads/month
7	flet Web-based	282,934	16,671	2026-09-14	Web-based GUI Development CLI & GUI	→
	Cross-platform GUI framework for building modern apps in pure Python.
	flet-dev/github.com/flet-dev/flet /2026-09-14 /282,934 downloads/month
8	kivy Desktop	218,348	19,015	2026-09-13	Desktop GUI Development CLI & GUI	→
	A library for creating NUI applications, running on Windows, Linux, Mac OS X, Android and iOS.
	kivy/github.com/kivy/kivy /2026-09-13 /218,348 downloads/month
9	dearpygui Desktop	184,843	15,615	2026-05-13	Desktop GUI Development CLI & GUI	→
	A Simple GPU accelerated Python GUI framework
	hoffstadt/github.com/hoffstadt/DearPyGui /2026-05-13 /184,843 downloads/month
10	wxPython Desktop	163,321	2,625	2026-09-09	Desktop GUI Development CLI & GUI	→
	A blending of the wxWidgets C++ class library with the Python.
	wxWidgets/github.com/wxWidgets/Phoenix /2026-09-09 /163,321 downloads/month
11	toga Desktop	14,393	5,414	2026-09-14	Desktop GUI Development CLI & GUI	→
	A Python native, OS native GUI toolkit.
	beeware/github.com/beeware/toga /2026-09-14 /14,393 downloads/month
12	gooey Wrappers	6,405	21,903	2026-03-12	Wrappers GUI Development CLI & GUI	→
	Turn command line programs into a full GUI application with one line.
	chriskiehl/github.com/chriskiehl/Gooey /2026-03-12 /6,405 downloads/month
13	tkdesigner Tkinter	461	10,264	2026-09-05	Tkinter GUI Development CLI & GUI	→
	Generates Tkinter interfaces from Figma designs using the Figma API.
	ParthJadhav/github.com/ParthJadhav/Tkinter-Designer /2026-09-05 /461 downloads/month
14	tkinter Tkinter	Stdlib	77,167	2026-09-14	Tkinter GUI Development CLI & GUI Stdlib	→
	(Python standard library) The standard Python interface to the Tcl/Tk GUI toolkit.
	python/docs.python.org/3/library/tkinter.html /2026-09-14

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