Web APIs Python Libraries - Awesome Python

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Row number					Tags
1	fastapi Framework Agnostic	490,750,535	102,099	2026-09-01	Framework Agnostic Web APIs Web Development	→
	A modern, fast, web framework for building APIs with standard Python type hints.
	fastapi/github.com/fastapi/fastapi /2026-09-01 /490,750,535 downloads/month
2	grpcio RPC	380,070,210	45,297	2026-09-05	RPC Web APIs Web Development	→
	HTTP/2-based RPC framework with Python bindings, built by Google.
	grpc/github.com/grpc/grpc /2026-09-05 /380,070,210 downloads/month
3	django-rest-framework Django	26,013,385	30,163	2026-09-05	Django Web APIs Web Development	→
	A powerful and flexible toolkit to build web APIs.
	encode/github.com/encode/django-rest-framework /2026-09-05 /26,013,385 downloads/month
4	connexion Framework Agnostic	7,439,184	4,612	2026-04-25	Framework Agnostic Web APIs Web Development	→
	A spec-first framework that automatically handles requests based on your OpenAPI specification.
	spec-first/github.com/spec-first/connexion /2026-04-25 /7,439,184 downloads/month
5	strawberry Framework Agnostic	6,736,473	4,712	2026-09-05	Framework Agnostic Web APIs Web Development	→
	A GraphQL library that leverages Python type annotations for schema definition.
	strawberry-graphql/github.com/strawberry-graphql/strawberry /2026-09-05 /6,736,473 downloads/month
6	django-ninja Django	3,198,975	9,182	2026-09-03	Django Web APIs Web Development	→
	Fast, Django REST framework based on type hints and Pydantic.
	vitalik/github.com/vitalik/django-ninja /2026-09-03 /3,198,975 downloads/month
7	strawberry-django Django	1,894,378	504	2026-09-02	Django Web APIs Web Development	→
	Strawberry GraphQL integration with Django.
	strawberry-graphql/github.com/strawberry-graphql/strawberry-django /2026-09-02 /1,894,378 downloads/month
8	apiflask Flask	190,327	1,136	2026-08-15	Flask Web APIs Web Development	→
	A lightweight Python web API framework based on Flask and Marshmallow.
	apiflask/github.com/apiflask/apiflask /2026-08-15 /190,327 downloads/month
9	django-modern-rest Django	24,003	1,423	2026-09-05	Django Web APIs Web Development	→
	Modern REST with speed, types, async, `msgspec`, `pydantic` and other goodies!
	wemake-services/github.com/wemake-services/django-modern-rest /2026-09-05 /24,003 downloads/month

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