Web APIs Python Libraries - Awesome Python

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Row number					Tags
1	fastapi Framework Agnostic	394,277,586	102,369	2026-09-01	Framework Agnostic Web APIs Web Development	→
	A modern, fast, web framework for building APIs with standard Python type hints.
	fastapi/github.com/fastapi/fastapi /2026-09-01 /394,277,586 downloads/month
2	grpcio RPC	324,332,719	45,314	2026-09-16	RPC Web APIs Web Development	→
	HTTP/2-based RPC framework with Python bindings, built by Google.
	grpc/github.com/grpc/grpc /2026-09-16 /324,332,719 downloads/month
3	django-rest-framework Django	23,734,750	30,182	2026-09-15	Django Web APIs Web Development	→
	A powerful and flexible toolkit to build web APIs.
	encode/github.com/encode/django-rest-framework /2026-09-15 /23,734,750 downloads/month
4	strawberry Framework Agnostic	5,878,864	4,716	2026-09-16	Framework Agnostic Web APIs Web Development	→
	A GraphQL library that leverages Python type annotations for schema definition.
	strawberry-graphql/github.com/strawberry-graphql/strawberry /2026-09-16 /5,878,864 downloads/month
5	connexion Framework Agnostic	5,490,893	4,612	2026-04-25	Framework Agnostic Web APIs Web Development	→
	A spec-first framework that automatically handles requests based on your OpenAPI specification.
	spec-first/github.com/spec-first/connexion /2026-04-25 /5,490,893 downloads/month
6	django-ninja Django	3,024,010	9,192	2026-09-14	Django Web APIs Web Development	→
	Fast, Django REST framework based on type hints and Pydantic.
	vitalik/github.com/vitalik/django-ninja /2026-09-14 /3,024,010 downloads/month
7	strawberry-django Django	1,733,422	504	2026-09-16	Django Web APIs Web Development	→
	Strawberry GraphQL integration with Django.
	strawberry-graphql/github.com/strawberry-graphql/strawberry-django /2026-09-16 /1,733,422 downloads/month
8	apiflask Flask	181,541	1,137	2026-09-12	Flask Web APIs Web Development	→
	A lightweight Python web API framework based on Flask and Marshmallow.
	apiflask/github.com/apiflask/apiflask /2026-09-12 /181,541 downloads/month
9	django-modern-rest Django	22,117	1,458	2026-09-16	Django Web APIs Web Development	→
	Modern REST with speed, types, async, `msgspec`, `pydantic` and other goodies!
	wemake-services/github.com/wemake-services/django-modern-rest /2026-09-16 /22,117 downloads/month

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